Mental Fatigue, Fatigue, and Depression can present symptoms that can be mistaken for each other.

All of them bring symptoms of extreme tiredness even with a proper diet and a good night’s rest and unfortunately, they can coexist in a loop that reinforces the symptoms and the condition itself.

It can be said that depression occurs when a person feels sad, anxious or hopeless for an extended period of time. This condition has very high impact on energy levels, making the decrease of energy, mental fatigue, and fatigue as one of the most visible symptoms, but we cannot forget some of the less obvious ones such as:

  • Headaches. These are fairly common in people with depression. If you already had migraine headaches, they may become worse if you're depressed;

  • Exhaustion and fatigue. No matter how much you sleep, you may still feel tired or worn out. Getting out of the bed in the morning may seem very hard, even impossible;

  • Trouble concentrating and making decisions.

These are only some examples of the many symptoms that affect the body of one with depression and can be easily mistaken with Fatigue or Chronic Fatigue. Some cases when caught early are limited to mental fatigue and can be managed easier, reduced and even prevented. Chronic fatigue syndrome is a condition that causes a person to have continuous feelings of fatigue without any underlying cause.

When fatigue becomes a chronic condition, some other symptoms start to be seen, such as joint pain, muscle pain, and sore throat. Unfortunately, people who have chronic fatigue syndrome may become depressed. And while depression doesn’t cause chronic fatigue syndrome, it can certainly cause increased fatigue.

When Fatigue or Mental Fatigue sets in, Anxiety escalates rapidly out of despair for not being able to do what was once so easy. The task of reframing negative thoughts and feelings into positive ones is a titanic task.


In the Office Environment, Mental Fatigue can be measured and managed so it can be tackled by the HR team or Managing team and reduce office absenteeism based on Mental Fatigue or other pathologies that can be reinforced by all the stressors present. It is possible to clearly detect fatigue and mental fatigue in very early stages and this can be an early sign of alert for other pathologies that can be tackled early on with less symptoms and less impact on the employee’s live quality and productivity.